Friday, November 9, 2012

Theories of Aging

There are many theories about how we age. Is aging a disease or an inevitable process that all biological creatures must experience, or can it be prevented?

Intrinsic aging defines the natural signs of aging as a genetic process.
Extrinsic aging refers to the visible signs of aging as a genetic process.

Internal and external factors directly relate to two separate groups of aging theories.

1) preprogrammed Aging that is due to genetic factors.  It suggests that aging is determined by a predetermined biological clock that starts at conception, and that genes play a strong role in the aging process.
Theories associated with preprogrammed theory include- Programmed Longevity, Telomerase Theory, Immunological Theory, Pacemaker Theory, Genetic Theory.

2) Damage-Based Theories- These theories refer to aging that is influenced by environmental or lifestyle factors that cause damage to cells and body systems.  These theories focus on the damage that happens at the molecular level then move outward.
  • Free Radical Theory- states that aging is caused by accumulated free radicals attacking the DNA, proteins, and fats of living cells, causing cell death.
  • Membrane Theory- states it is the damage done by free radicals in the cell membrane that causes change in the cell's ability to transfer chemicals, heat, and electricity.
  • Cross Linking Theory- (Glycation) Relates to the binding of protein and simple sugars (glucose) to protein.  When cross linking occurs, protein is damaged and unable to perform as intended.  The result is thick, dry,sagging, yellow skin.
  • Wear & Tear Theory- indicates the war and tear on our whole body system accelerates the aging process.  This theory lead the way to the free radical and cross linking theory.
  • Inflammation Theory- This theory is new.  It states that chronic inflammation result in accumulated damage to the body.  The theory explains that the inflammation cascade is a long strenuous process on the body, cells and tissue.  Once the inflammation cascade is started it should end when the immune response is activated without an invader or does not receive the signal from T-cells that tells the immune cells to stop.
Conclusion
If we take a cross-section of all the theories you can see that no one theory is independent of the other.  They all lead to aging.  We cannot always see the decline of our bodies, but eventually all damage will become apparent.  Depending on your theories about aging changes how you approach treating clients.  If you believe in the pre-programmed approach, you have to ask yourself can we even help aging skin?   The reality is that no one theory can stand on its own, they depend upon one another.
What is your opinion?
Resource-  Milady's Aesthetician Series, Aging Skin, Susanne Schmaling.

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